Detecting recurrent extinction in a metapopulation of Anopheles gambiae: preliminary results using simulation

نویسندگان

  • NICHOLAS C. MANOUKIS
  • YOOSOOK LEE
  • EDGAR E. VALLEJO
  • CHARLES E. TAYLOR
چکیده

In this paper we present a method for studying recurrent extinction in a metapopulation of Anopheles gambiae. We model the metapopulation as a collection of populations, in which individuals are represented as haploid DNA sequences that evolve through mutation, genetic drift and clonal replication. Analysis of simulation results demonstrates the potential of repeated measurements of Watterson’s θ for discriminating hypotheses of population structure. These results demonstrate that simulation is an appropriate methodology for studying population genetic questions in biology. Key-Words : Anopheles gambiae, Mali, modeling, simulation, genetic diversity, metapopulation

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تاریخ انتشار 2004